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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Dexamethasone
supplement:
Glutamic Acid
Research Papers that Mention the Interaction
“GCs, including corticosterone, corticosterone-sulfate, hydrocortisone-hemisuccinate and dexamethasone 21-phosphate(DEX) were found stimulating Glu uptake.”
Rapid enhancement of high affinity glutamate uptake by glucocorticoids in rat cerebral cortex synaptosomes and human neuroblastoma clone SK-N-SH: possible involvement of G-protein.“Furthermore, compared with the GLU group, the CD11b/c protein expression significantly decreased in the group treated simultaneously with DEX and GLU and the group treated with DEX after GLU stimulation.”
[Dexamethason suppresses the activation of rat microglia induced by glutamic acid].“Concommitantly, results of quantitative analysis in the dexamethasone group revealed statistically extremely significant higher amino acid values for glutamic acid , aspartic acid, beta-alanine, and lysine and significantly higher values for gamma-aminobutyric acid, glutamine, glycine, and serine when compared to the nondexamethasone group.”
“These findings suggested that the preventive use of dexamethasone in large dosage would reduce the binding of Glu , and could possibly protect the brain tissues from damage in HIE.”
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