Possible Interaction: Dexamethasone and Epinephrine

“Nebulized racemic epinephrine given with an appropriate device is also effective, but the effect of epinephrine is less remarkable in patients treated with dexamethasone.”

“ Dexamethasone reduced urinary epinephrine to a greater extent during altitude exposure (from 9.41 ng.mg-1 creatinine with placebo to 4.16 with dexamethasone) when compared with sea level (from 3.24 to 3.08).”

“ Dexamethasone exposure for 30 min enhanced the adrenaline effect both in sportsmen and trained rats.”

“A combination of bupivacaine, epinephrine , and dexamethasone can prolong the duration of efficient analgesia of all relevant nerves after TKA and makes the use of catheter infusion redundant.”

“When to become pregnant, treatment with hydrocortisone or dexamethasone can limit the production of adrenal androgens and progesterone and improves spontaneous pregnancy rates while minimizing the risk of miscarriage, which is usually relatively high in this disease.”

“AIM It has been suggested that a 6-day dexamethasone course combined with adrenaline may significantly reduce the admission rate in outpatients.”

“Combined dexamethasone and epinephrine may reduce outpatient admissions, but results are exploratory and safety data limited.”

“The combination of oral dexamethasone with nebulised epinephrine potentially decreases the need for hospitalisation, while nebulised 3% hypertonic saline mixed with a bronchodilator decreases the length of hospitalisation.”

“You know that there is no evidence for the use of bronchodilators or corticosteroids in bronchiolitis, but you wonder whether the combination of dexamethasone and epinephrine could help your patient to recover more quickly.”

“We read with great interest the study by Sumner et al,1 who showed that among infants 1.5 to 12 months of age with bronchiolitis treated in the emergency department, combined therapy with dexamethasone and epinephrine may significantly reduce hospital admissions and is more cost-effective than …”