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Last Updated: 4 months ago

Possible Interaction: Dexamethasone and Alpha-Ketoglutarate

Research Papers that Mention the Interaction

Impairment caused by Dex in presented long bones animal model was prevented by dietary supplementation with 2-Ox and vast majority of assessed bone parameters were restored almost to the control level.
Experimental biology and medicine  •  2017  |  View Paper
Alpha-ketoglutarate administered to … influence of dexamethasone lowered the total cholesterol concentration by 40%, and enhanced aspartate by 41%, serine by 76%, glutamate by 105%, glutamine by 36%, … arginine by 105%, as well as methionine and cystathionine, but increased the sulphur concentration compared with the control (p < 0.01).
Postnatal administration of AKG had a protective effect on liver structure, and lowered the total cholesterol concentration in piglets prenatally exposed to dexamethasone , and also influenced selected macro- and microelement serum concentrations and amino acids plasma concentration.
Journal of animal physiology and animal nutrition  •  2009  |  View Paper
Dexamethasone treatment produced significant decreases in the lung concentrations of glutamine (47.2%), glutamate (30.9%) and 2-oxoglutarate (57.3%).
Clinical science  •  1991  |  View Paper
Dexamethasone treatment produced significant decreases in the concentrations of skeletal muscle glutamine (51.8%) and 2-oxoglutarate (50.8%).
Clinical science  •  1990  |  View Paper
The … of dexamethasone to the culture medium induced a three- to … increase in the specific activity of tyrosine alpha-ketoglutarate transaminase ; this increase was inhibited by the simultaneous addition of cycloheximide or actinomycin D. The …, when added to cells given prior treatment with dexamethasone, further enhanced the transaminase activity.
Science  •  1970  |  View Paper