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Last Updated: a month ago

Possible Interaction: Dexamethasone and Alpha-Ketoglutarate

Research Papers that Mention the Interaction

Impairment caused by Dex in presented long bones animal model was prevented by dietary supplementation with 2-Ox and vast majority of assessed bone parameters were restored almost to the control level.
Experimental biology and medicine  •  2017  |  View Paper
Alpha-ketoglutarate administered to … influence of dexamethasone lowered the total cholesterol concentration by 40%, and enhanced aspartate by 41%, serine by 76%, glutamate by 105%, glutamine by 36%, … arginine by 105%, as well as methionine and cystathionine, but increased the sulphur concentration compared with the control (p < 0.01).
Postnatal administration of AKG had a protective effect on liver structure, and lowered the total cholesterol concentration in piglets prenatally exposed to dexamethasone , and also influenced selected macro- and microelement serum concentrations and amino acids plasma concentration.
Journal of animal physiology and animal nutrition  •  2009  |  View Paper
CONCLUSION The bone mineral density and mechanical and geometric properties of humeri indicate an inverse effect of maternal separate or simultaneous administration of AKG and Dex to sows on bone development during the last 24 days of prenatal life.
CONCLUSION The bone mineral density and mechanical and geometric properties of humeri indicate an inverse effect of maternal separate or simultaneous administration of AKG and Dex to sows on bone development during the last 24 days of prenatal life.
Simultaneous administration of Dex and AKG significantly increased the analyzed properties of humeri.
Simultaneous administration of Dex and AKG significantly increased the analyzed properties of humeri.
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians  •  2006  |  View Paper
Dexamethasone treatment produced significant decreases in the lung concentrations of glutamine (47.2%), glutamate (30.9%) and 2-oxoglutarate (57.3%).
Clinical science  •  1991  |  View Paper
Dexamethasone treatment produced significant decreases in the concentrations of skeletal muscle glutamine (51.8%) and 2-oxoglutarate (50.8%).
Clinical science  •  1990  |  View Paper
The … of dexamethasone to the culture medium induced a three- to … increase in the specific activity of tyrosine alpha-ketoglutarate transaminase ; this increase was inhibited by the simultaneous addition of cycloheximide or actinomycin D. The …, when added to cells given prior treatment with dexamethasone, further enhanced the transaminase activity.
Science  •  1970  |  View Paper