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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Deslanoside and Serotonin

supplement:

Deslanoside

Research Papers that Mention the Interaction

This increase in free serotonin in plasma caused by inhibition of uptake may play a role in the cardiotoxicity of deslanoside.
Archives internationales de pharmacodynamie et de therapie  •  1979  |  View Paper
In addition, the dose of deslanoside to produce ventricular fibrillation in these animals was significantly correlated with the increase in ventricular pacemaker rate seen during th 5-HT infusion in the presence of deslanoside.
Studies were also performed to determine whether the arrhythmogenic interaction of serotonin with deslanoside was associated with alterations in either cardiac tissue, blood or plasma levels of serotonin and 5-hydroxyindoleacetic acid.
These results suggest that exogenous serotonin interacts with deslanoside to enhance the arrhythmogenic action of deslanoside.
European journal of pharmacology  •  1978  |  View Paper