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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
drug:
Desipramine
supplement:
Quinidine
Research Papers that Mention the Interaction
“In addition, the method was applied to the CYP2D6-mediated desipramine-quinidine interaction: the predicted 6.4-fold increase of desipramine AUC by quinidine was consistent with the observed 6.7-fold increase of AUC in the clinical drug-drug interaction study.”
A novel approach to the prediction of drug-drug interactions in humans based on the serum incubation method.“Both activities of desipramine and imipramine 2-hydroxylase were markedly inhibited by quinidine but not by quinine.”
“Thus both quinidine and quinine decreased the excretion of 2‐OH‐DMI.”
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