supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
drug:
Desipramine
supplement:
Potassium
Research Papers that Mention the Interaction
“Reversed perfusion with high potassium in the presence of 2 μM desipramine induced the release of norepinephrine.”
Regulation of norepinephrine release from the rat bed nucleus of the stria terminalis: In vivo microdialysis studies“Moderate increases in O2 consumption induced by low concentrations of potassium were potentiated by desipramine , a drug which is known to block the uptake of catecholamines by adrenergic nerve endings.”
“1) Antagonism of the response of the vas deferens to potassium occurs with concentrations of protriptyline and DMI which were 1/100 to 1/200 of those necessary to produce local anesthesia, whereas cocaine and lidocaine antagonize potassium-induced contractions in concentrations which produce local anesthesia.”
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback