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“There is marked difference between male and female rats in the demethylation of I. The brain levels of demethylimipramine (DMI) shortly after administration of I are much higher in the males than in the females.”
International review of neurobiology • 1966 | View Paper
“Moreover, micromolar concentrations of CLOM, DMI and NORF caused significant inhibitions of the activities of mitochondrial complexes ( I , II/III and IV).”