supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
drug:
Desipramine
supplement:
Glycine
Research Papers that Mention the Interaction
“In piglets, N and AA ileal losses were similar between periods, except for period 2, where losses per kg DMI were about 47 and 64% higher for glycine and proline, respectively (p < 0.05).”
Endogenous ileal losses of nitrogen and amino acids in pigs and piglets fed graded levels of casein“Repeated administration of the tricyclic antidepressant, desipramine , for 28 days to mice effected a decrease in the potency of glycine to displace [3H]5,7-dichlorokynurenic acid (5,7-DCKA) in mouse cortical homogenates.”
“Some noradrenaline uptake inhibiting ADS desipramine and viloxazine, but not maprotiline) were also significantly more effective in decreasing immobility time when combined with GLY than when administered alone.”
“Thus at the IC50 for GABA, p‐chloromercuriphenylsulphonate, chlorpromazine, prochlorperazine, iprindole, desmethylimipramine , apomorphine and diphenylhydramine also inhibited the uptake of radioactive glycine , alanine, noradrenaline, and 5‐hydroxytryptamine.”
“ Desipramine inw x creased the IC50 of glycine to displace H 5,7-DCKA Ž .”
Corrigendum to: "Noradrenergic lesion antagonizes desipramine-induced adaptation of NMDA receptors"
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback