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Try: Ginkgo, Methotrexate, Glucosamine

Last Updated: 3 years ago

Possible Interaction: Dehydroepiandrosterone and Temozolomide

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supplement:

Dehydroepiandrosterone

drug:

Temozolomide

Research Papers that Mention the Interaction

“Flow cytometry showed that DHEA plus TMZ pretreatment significantly increased apoptosis rate (P < 0.05).”

“MTT assays showed that DHEA plus temozolomide (TMZ) pretreatment significantly inhibited cell proliferation rate (P < 0.05).”

Relationship between CYP17A1-Mediated DNA Demethylation and Proliferation, Invasion and Metastasis of Glioma Cells.

Critical reviews in eukaryotic gene expression • 2020 | View Paper

“We found that as gliomas became more malignant, both CYP17A1 and DHEA were significantly upregulated in temozolomide (TMZ)-resistant cells and highly invasive cells.”

Upregulation of CYP17A1 by Sp1-mediated DNA demethylation confers temozolomide resistance through DHEA-mediated protection in glioma

Oncogenesis • 2017 | View Paper

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