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Discover Supplement-Drug Interactions

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Last Updated: 5 months ago

Possible Interaction: Dehydroepiandrosterone Sulfate and Pregnenolone

Research Papers that Mention the Interaction

Addition of pregnenolone on the first day of cultivation caused an increase in DHAS ( dehydroepiandrosterone sulphate ) and pregnenolone sulphate secretion during the first cultivation days, but no significant increase in cortisol production was noted.
Journal of steroid biochemistry  •  1979  |  View Paper
These findings indicate that DHEAS affects steroid hormone biosynthesis on a molecular level resulting in an increased formation of pregnenolone.
PloS one  •  2014  |  View Paper
DHEAS administration augmented concentrations of DHEA, pregnenolone , androstendiol and androstentriol in both brain structures, while androsterone injections increased brain levels of androsterone, epiandrosterone, 5α-dihydrotestosterone, and androstandiol.
Acta neurobiologiae experimentalis  •  2012  |  View Paper