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“Abstract Recent studies have demonstrated that neuropeptide Y (NPY) reduced the neural production of dehydroepiandrosterone (DHEA) in frog hypothalamic explants.”
“Co-administration of DHEA along with NPY blocked this NPY dependent effect.”
“These results suggest that DHEA blocks the over-eating in satiated rats induced by NPY.”
“Pulse-chase experiments with 35S-labeled 3′-phosphoadenosine 5′-phosphosulfate as a sulfate donor demonstrated that frog NPY (fNPY) inhibited the conversion of [3H]Δ5P and [3H]dehydroepiandrosterone ([3H]DHEA) into [3H,35S]Δ5PS and [3H,35S...”