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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Dehydroepiandrosterone
drug:
Miconazole
Research Papers that Mention the Interaction
“ER antagonists ICI 182,780 (fulvestrant) and 4-hydroxytamoxifen, general P450 inhibitor miconazole , and aromatase inhibitor exemestane inhibited activation by DHEA or metabolites in transfected cells.”
DHEA metabolites activate estrogen receptors alpha and beta“In both species, DHEA was extensively metabolized to multiple products; formation of these products was potently inhibited in both species by miconazole , demonstrating a principal role for cytochrome P450.”
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