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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Dehydroepiandrosterone and Haloperidol

Research Papers that Mention the Interaction

This potentiating effect of DHEA was suppressed by the selective sigma 1 antagonist NE-100 and by the non-selective sigma antagonist haloperidol.
The Journal of endocrinology  •  1996  |  View Paper
The effect of DHEA was reversed by the selective sigma antagonist N-dipropyl-2-(4-methoxy-3- (2-phenylethoxy)phenyl)- ethylamine monohydrochloride (NE-100) and by haloperidol , but not by spiperone.
The Journal of neuroscience : the official journal of the Society for Neuroscience  •  1996  |  View Paper
The sigma antagonists haloperidol and 1-[2-(3,4-dichlorophenyl)-ethyl]-4-methylpiperazine, although inactive by themselves, completely prevented the effects of DHEA S , PREG S, and 1,3-di(2-tolyl)guanidine on NMDA-evoked [3H]NE release.
Proceedings of the National Academy of Sciences of the United States of America  •  1995  |  View Paper