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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Dehydroepiandrosterone
drug:
Glycyrrhetinic Acid
Research Papers that Mention the Interaction
“Basal and forskolin-stimulated syntheses of deoxycorticosterone … inhibited in a dose-dependent manner; glycyrrhetinic acid inhibited … and dehydroepiandrosterone with IC50 values of 7 μM. Inhibition of deoxycorticosterone and dehydroepiandrosterone conjugation was apparent within 4 … acid treatment and was not associated with changes in the expression of SULT 2A1 mRNA.”
Liquorice and glycyrrhetinic acid increase DHEA and deoxycorticosterone levels in vivo and in vitro by inhibiting adrenal SULT2A1 activity
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