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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
supplement:
Dehydroepiandrosterone
supplement:
Glycerol
Research Papers that Mention the Interaction
“Dehydroepiandrosterone DHEA ) reduces body fat in rodents and humans, and increases glycerol release from isolated rat epididymal adipocytes and human visceral adipose tissue explants.”
Fat-reducing effects of dehydroepiandrosterone involve upregulation of ATGL and HSL expression, and stimulation of lipolysis in adipose tissue“Incorporation of [3H]glycerol into diacylglycerol was increased 150% above basal level for 20 min after stimulation with 1 microM DHEA.”
“Urea, glycerol , high pH and increased temperature were found to reverse the inhibition by dehydroepiandrosterone , suggesting alterations in the three-dimensional structure of the enzyme and the removal of the steroid-binding site from the proximity of the active centre.”
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