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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Dehydroepiandrosterone
drug:
Gaba Agents
Research Papers that Mention the Interaction
“The 3alpha,5alpha- and 3alpha,5beta-reduced derivatives of progesterone, deoxycorticosterone, dehydroepiandrosterone and testosterone enhance GABAergic neurotransmission and produce inhibitory neurobehavioral and anti-inflammatory effects.”
Simultaneous quantification of GABAergic 3α,5α/3α,5β neuroactive steroids in human and rat serum“These findings demonstrate that decreased concentrations of DHEAS together with increased brain concentrations of ALLO increase GABAergic tonic currents synergistically; suggesting that reduced brain DHEAS could further increase GABAergic tone in human HE.”
“ DHEA could act by reducing inhibitory GABAergic activity in the striatal output pathways.”
DHEA improves symptomatic treatment of moderately and severely impaired MPTP monkeys
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