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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Dehydroepiandrosterone and Dutasteride

Research Papers that Mention the Interaction

Salivary glands contained type I 5-α-reductase, and its inhibition with dutasteride completely blocked the upregulating effect of DHEA , but not of DHT, on CRISP-3 in human salivary gland acinar cells.
The effect of DHEA on CRISP-3 is indirect and is inhibited by dutasteride , showing that there is intracrine processing of DHEA in salivary glands.
The Journal of Rheumatology  •  2008  |  View Paper