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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Dehydroepiandrosterone and Collagenases

Research Papers that Mention the Interaction

CAT assay revealed that treatment with 10(-5) M DHEA resulted in a strong ( approximately 70%) inhibition of the collagenase promoter activity.
The steady-state levels of collagenase mRNA decreased in response to DHEA by 40%, whereas those of stromelysin-1 mRNA increased up to 2.4-fold, compared to controls.
Journal of dermatological science  •  2000  |  View Paper