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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Dehydroepiandrosterone and Calcium Supplement

Research Papers that Mention the Interaction

This study demonstrates that DHEA induced lysis of human red blood cells (RBCs) in a concentration-dependent manner, with ca.
Life sciences  •  1997  |  View Paper
In permeabilized cells, DHEA suppressed the Ca <sup>2+</sup>-induced secretion.
Using bovine chromaffin cells, we found that DHEA inhibited catecholamine secretion and cytosolic Ca <sup>2+</sup> ([Ca<sup>2+</sup>]<sub>i</sub>) rise coupled with nicotinic acetylcholine receptor (nAChR) without exerting an effect on <sup>3</sup>H-nicotine binding.
Journal of Biomedical Science  •  2004  |  View Paper
Acute treatment with DHEA , but not with DHEA-S, significantly inhibited nitric oxide (NO) production and Ca2+ -sensitive NO synthase (NOS) activity caused by NMDA stimulation.
Journal of Pharmacology and Experimental Therapeutics  •  2004  |  View Paper
In PA smooth muscle cells, DHEA reduced the level of intracellular calcium (measured by microspectrofluorimetry).
Proceedings of the National Academy of Sciences of the United States of America  •  2003  |  View Paper
In this work, we demonstrated that calcium (Ca(+2)) is able to induce a conformational change in trans-dehydroandrosterone (DHEA).
Steroids  •  2015  |  View Paper