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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Dehydroepiandrosterone
drug:
Becaplermin
Research Papers that Mention the Interaction
“Only MAPK activation induced by PDGF-BB was reduced by pretreatment with DHEA , although DHEA did not affect the MAPK activation induced by EGF or bFGF.”
“The increase of cAMP by PDGF-BB was augmented by pretreatment with DHEA , although DHEA alone did not affect cAMP.”
“These results suggest that DHEA inhibited MAPK activation induced by PDGF-BB via PGE2 overproduction and subsequent cAMP-dependent pathway in human male aortic SMCs.”
Effects of dehydroepiandrosterone on mitogen-activated protein kinase in human aortic smooth muscle cells.
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