Possible Interaction: Dehydroascorbic Acid and Resveratrol

“In this paper, the competitive inhibition of intracellular uptake of glucose and dehydroascorbic acid in U937 and HL-60 cells by resveratrol is reported.”

“Furthermore, RSV-induced enrichment of intracellular AsA levels was completely … a GLUT inhibitor cytochalasin B. These results suggest that RSV can potentiate intracellular AsA … activation of the DHA transport and subsequent intracellular reduction from DHA to AsA. Thus, RSV … useful for maintaining substantial AsA accumulation in the skin keratinocytes.”

“Our results demonstrate that RSV treatment could significantly enhance intracellular VC levels after either AsA or DHA supplementation, and intracellular VC accumulated mainly as AsA. Our results also indicate that most of the intracellular transported DHA was reduced to AsA and accumulated after uptake into cells.”