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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Dehydroascorbic Acid
supplement:
Myricetin
Research Papers that Mention the Interaction
“In Jurkat cells, two potent flavonoids myricetin and quercetin) competitively inhibited dehydroascorbic acid uptake, and K(i) values were approximately 14 and 15 micromol/L, respectively.”
“ Myricetin at concentrations of 22 and 18 micromol/L, respectively, inhibited half of dehydroascorbic acid uptake in the cells overexpressing GLUT 1 and GLUT 3.”
Intracellular accumulation of ascorbic acid is inhibited by flavonoids via blocking of dehydroascorbic acid and ascorbic acid uptakes in HL-60, U937 and Jurkat cells.“We herein report that the flavonoids quercetin and myricetin , while inhibiting dehydroascorbic acid uptake-and thus the erythrocyte ascorbic acid content-effectively stimulate the extracellular reduction of ferricyanide.”
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