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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Dehydroascorbic Acid
drug:
Insulin
Research Papers that Mention the Interaction
“Preincubation of oocytes for >4 h with insulin (1 micrometer) augmented GLUT4 transport of 2-DG and DHA by up to 5-fold.”
“Preincubation with insulin (0.67 micrometer) increased transport of each substrate similarly: 7-10-fold for 2-DG and 6-8-fold for DHA.”
Dehydroascorbic acid transport by GLUT4 in Xenopus oocytes and isolated rat adipocytes.“ Insulin increased the intracellular concentration of ascorbate derived from DHAA and also increased the initial rates of uptake of DHAA and 2-deoxyglucose, but not that of ascorbate.”
“We conclude that insulin and IGF-I stimulate osteoblastic uptake of DHAA through facilitative hexose transporters.”
“ Dehydroascorbic acid also increased the leakage of insulin from islet tissue.”
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