supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
supplement:
Dehydroascorbic Acid
supplement:
Epigallocatechin
Research Papers that Mention the Interaction
“Among these four flavanols, EGCG exerted the strongest trapping efficacy by capturing approximate 80% of DASA within 60 min.”
“In the present study, we demonstrated for the first time that four tea flavanols, (-)-epigallocatechin 3-O-gallate (EGCG), (-)-epigallocatechin (EGC), (-)-epicatechin 3-O-gallate (ECG), and (-)-epicatechin (EC), could significantly trap DASA and consequently form 6C- or 8C-ascorbyl conjugates.”
Tea Flavanols Block Advanced Glycation of Lens Crystallins Induced by Dehydroascorbic Acid.“Results shows the dual function of AA, protect action at low concentration and promoting degradation at high concentration, and the critical concentration is about … the reversible reaction from AA to DHAA inhibiting oxidation pathway of EGCG to EGCG quinone or other activated intermediates, and both AA and DHAA … EGCG.”
Dual effects of ascorbic acid on the stability of EGCG by the oxidation product dehydroascorbic acid promoting the oxidation and inhibiting the hydrolysis pathway.
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback