Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
“The …) and DFO (40–60 mg/kg, at least … an increase in cardiac (mean ± SE =30.2 ± 2.3, range 22–41 ms) and liver (mean ± SE =27.6 ± 2.8, range … reduction in serum ferritin (mean ± SE = 158 ± 49, range 40–421 μg/L) to within the NRBISL.”
“Further, it was found that pretreatment with selenium and vitamin E, both antioxidants, and deferoxamine , a specific iron chelator, significantly inhibited lipid peroxidation as well as liver cell damage.”
Toxicology and applied pharmacology • 1994 | View Paper
“Preincubation with 0.4 mM deferoxamine conferred 67 +/- 15% (mean +/- SE ) protection from LPS-induced cytotoxicity but 48 h of preincubation were required to induce significant protection.”