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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Deferoxamine
supplement:
NADH
Research Papers that Mention the Interaction
“The decrease in the activity of glucose 6-phosphatase generated by NADH was prevented by using desferrioxamine , an irreversible ferric chelator, butylated hydroxytoluene and Trolox, two agents which inhibit lipid peroxidation, and reduced glutathione, a non-specific radical scavanger.”
Possible role of free radicals generated by pseudohypoxia in the regulation of hepatic glucose output. An in vitro model using rat liver microsomal glucose 6-phosphatase“The iron chelators EDTA (ethylenediaminetetraacetic acid) and DFA deferoxamine melysate ) at high concentrations (2 mM) inhibited the NADH oxidation, whereas they were ineffective at lower concentrations (80 microM); the subsequent addition of ferrous ions caused a rapid and limited increase of oxygen consumption which later ceased.”
Hydrogen peroxide formation and iron ion oxidoreduction linked to NADH oxidation in radish plasmalemma vesicles.
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