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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Deferoxamine Mesylate and Iron, Dietary

Research Papers that Mention the Interaction

The iron chelator deferoxamine mesylate DFO ) decreased the iron content in the bone, liver, and spleen, and significantly relieved unloading‐induced bone loss under HyMF reloading.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research  •  2019  |  View Paper
The iron chelator deferoxamine mesylate DFO ) reduced the iron content in bone and alleviated unloading-induced bone loss.
Bone  •  2017  |  View Paper
However, as shown earlier with IRP1, both desferrioxamine mesylate and succinyl acetone will inhibit the degradation of IRP2 induced by iron but not that induced by heme.
Studies have shown that the degradation of IRP1 that is induced by iron can be inhibited by either desferrioxamine mesylate (an iron chelator) or succinyl acetone (an inhibitor of heme synthesis), whereas the degradation induced by heme cannot.
The Journal of Biological Chemistry  •  1998  |  View Paper