supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
drug:
Deferoxamine
supplement:
Glycerol
Research Papers that Mention the Interaction
“ Deferoxamine , by interacting with Fenton reaction chemistry, and trimetazidine, by its anti-ischaemic and antioxidative properties, protected the kidney against the oxidative stress and the resultant renal dysfunction produced by glycerol.”
“ Glycerol treatment resulted in marked renal oxidative stress and deranged renal functions which significantly improved by trimetazidine and deferoxamine treatments.”
“group 3 was given glycerol plus trimetazidine (3 mg/kg), and groups 4 and 5 were given glycerol plus deferoxamine (50 and 100 mg/kg, respectively).”
Attenuation of Glycerol-Induced Acute Renal Failure in Rats by Trimetazidine and Deferoxamine“Certain iron chelators such as desferrioxamine , EDTA or diethylenetriaminepentaacetic acid, but not others such as ADP or citrate, inhibited glycerol oxidation.”
“Continuous infusion of deferoxamine beginning at the time of glycerol injection significantly attenuated this renal dysfunction.”
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback