Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago

Possible Interaction: Deferoxamine and Ferrous

supplement:

Ferrous

Research Papers that Mention the Interaction

We describe the protective effects of desferrioxamine against the deleterious effects of ferrous iron and relate this to its chelating and scavenging activity.
Agents and Actions  •  2005  |  View Paper
Lipid peroxidation dependent on Fe(II) autoxidation was stimulated by the addition of deferrioxamine.
The binding of either valence of iron by deferrioxamine may result in variable effects on iron-catalyzed processes, such as lipid peroxidation, either via slow binding of Fe(III) or the rapid binding of Fe(II) with concomitant Fe(II) oxidation.
Archives of biochemistry and biophysics  •  1992  |  View Paper
Addition of deferoxamine completely inhibited both ferrous ascorbate, 1:20 and ferric nitrilotriacetate-induced lipid peroxidation, demonstrating the requirement for iron for its stimulation.
Biochimica et biophysica acta  •  1988  |  View Paper