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Last Updated: 4 years ago

Possible Interaction: Deferasirox and Vitamin C

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drug:

Deferasirox

supplement:

Vitamin C

Research Papers that Mention the Interaction

“We conclude that vitamin C status modulates the release of iron from the reticuloendothelial system and correlates positively with DFX chelation efficiency.”

Ascorbate status modulates reticuloendothelial iron stores and response to deferasirox iron chelation in ascorbate-deficient rats.

Experimental hematology • 2012 | View Paper

“ Deferasirox showed the greatest antioxidant activity in the oxidation of ascorbic acid with the participation of iron ions and reduced the reaction rate by about a 100 times.”

Antioxidant Activity of Deferasirox and Its Metal Complexes in Model Systems of Oxidative Damage: Comparison with Deferiprone

Molecules • 2021 | View Paper

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