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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Decitabine and Sulforaphane

supplement:

Sulforaphane

Research Papers that Mention the Interaction

Accordingly, we explored whether a low dose of the antioxidant sulforaphane SFN ) in combination with the epigenetic drug 5-aza-2’-deoxycytidine (DAC) could slow melanoma cell growth.
Methods: Melanoma cell growth characteristics, gene transcription profiles, and histone epigenetic modifications were measured after single and combination treatments with SFN and DAC.
Results: We detected melanoma cell growth inhibition and specific changes in gene expression profiles upon combinational treatments with SFN and DAC , while no significant alterations in histone epigenetic modifications were observed.
Medicines  •  2019  |  View Paper