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Discover Supplement-Drug Interactions

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Last Updated: a year ago

Possible Interaction: Decitabine and Adrenocorticotropic Hormone

Research Papers that Mention the Interaction

Incubation with AZA did not exert an additional stimulatory effect on CRH-stimulated POMC and ACTH.ConclusionsThe present study shows that AZA increases POMC gene expression and ACTH secretion in human pituitary ACTH-secreting tumors.
ResultsIncubation with AZA increased constitutive POMC expression and ACTH secretion by human corticotrope adenomas.
This can be taken to indicate that mechanisms set into motion by AZA play a role in the regulation of ACTH secretion/POMC expression in tumoral corticotropes and paves the way to further studies in Cushing’s disease.
Pituitary  •  2013  |  View Paper