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Last Updated: 2 months ago

Possible Interaction: DCI and Epinephrine

drug:

DCI

supplement:

Epinephrine

Research Papers that Mention the Interaction

The observation that dichloroisoproterenol may block the positive inotropic effect of epinephrine , while only slightly reducing the positive inotropic effect of norepinephrine, may be used to differentiate between these two catecholamines.
Circulation research  •  1962  |  View Paper
The effect of epinephrine was blocked by single injections of the β blockers propranolol (10 mg/kg body weight) or dichloroisoproterenol 30 min before the hormone treatment.
Lipids  •  2006  |  View Paper
Dichloroisoproterenol inhibited the glycogenolytic, chronotropic, and inotropic effects of epinephrine ; veratramine prevented a rise above control cardiac rate without inhibiting the glycogenolytic effect of epinephrine.
The Journal of pharmacology and experimental therapeutics  •  1963  |  View Paper
DCI , in very low concentrations, selectively inhibited both chronotropic and inotropic responses to epinephrine.
The ability of various classical adrenergic blocking agents and of dichloroisoproterenol (DCI) to block the chronotropic and inotropic responses of the mammalian myocardium to epinephrine has been re-evaluated on isolated atria and papillary muscles.
The Journal of pharmacology and experimental therapeutics  •  1961  |  View Paper
The present investigation demonstrates that DCI almost completely abolishes the increase in blood glucose and free fatty acids produced by epinephrine , norepinephrine, and isoproterenol in the dog.
The Journal of pharmacology and experimental therapeutics  •  1961  |  View Paper
The effect of epinephrine was blocked by single injections of the beta blockers propranolol (10 mg/kg body weight) or dichloroisoproterenol 30 min before the hormone treatment.
Lipids  •  1978  |  View Paper
Dichloroisoproterenol , a beta -adrenergic blocking agent, competitively inhibits the changes in the epinephrine spectrum while its own spectrum exhibits evidence of binding.
Molecular pharmacology  •  1969  |  View Paper
Dichloroisoproterenol , at 1 mg/ml, inhibited the depressing effect of epinephrine at the previously mentioned dose, but had no effect on the depressing effect of progesterone.
Biochemical pharmacology  •  1968  |  View Paper
Pretreatment of rats with dichloroisoproterenol blocked the action of epinephrine upon diaphragm phosphorylase at pH 7.8 and 6.9.
The Journal of pharmacology and experimental therapeutics  •  1967  |  View Paper
Activation produced by a maximal dose of epinephrine (0.1 µg) was blocked by treatment of the hearts with the adrenergic blocking agents, dichloroisoproterenol and nethalide.
The Journal of biological chemistry  •  1966  |  View Paper
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