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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Daunorubicin and Tartaric Acid

Research Papers that Mention the Interaction

In conclusion, for the first time we demonstrated that TA increases the intestinal absorption of P-gp substrates Rho123 and daunorubicin , possibly by modulating the P-gp function without changing the expression level of P-gp in the rat intestine.
TA (20 mM) also increased the absorption of daunorubicin in the ileum, but TA (20 mM) did not change the expression level of P-glycoprotein (P-gp).
TA (20 mM) significantly inhibited excretion of i.v.-administered Rho123 and daunorubicin into the ileal lumen.
Drug metabolism and pharmacokinetics  •  2006  |  View Paper