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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Daunorubicin
supplement:
Folate
Research Papers that Mention the Interaction
“ Folate deprivation markedly increased growth inhibitory effects of the established MRP1 substrates daunorubicin (~twofold), doxorubicin (~fivefold), and methotrexate (~83-fold) in MRP1-overexpressing cells, proportional to MRP1 expression.”
Folates provoke cellular efflux and drug resistance of substrates of the multidrug resistance protein 1 (MRP1)
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