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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Daunorubicin and Cupric Cation

Research Papers that Mention the Interaction

Cu(II) and Mg(II) have different binding capacity with daunomycin , and have different combination mode with DNA.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy  •  2006  |  View Paper
In the presence of Cu 2+ , there is a reduction in the fluorescence intensity of the DNA— daunomycin complex , at pH values above 6·0.
In the visible region, at pH 5·2, the addition of Cu 2+ (10 −4 M) to a denatured DNA-daunomycin complex causes a spectral shift from 505 nm to 540 and 582 nm.
Biochemical pharmacology  •  1974  |  View Paper