Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 years ago

Possible Interaction: Daptomycin and Serum Albumin, Human

Research Papers that Mention the Interaction

Daptomycin was also found to bind to a single site on HSA , which was identified as site II.
To address this issue in more detail, we characterized the binding of daptomycin to plasma proteins and the findings indicate that the association constant for the binding of daptomycin to human serum albumin ( HSA ) is much higher than that for α1-acid glycoprotein, another plasma protein.
Journal of pharmaceutical sciences  •  2020  |  View Paper
Daptomycin ≥ 2 mg/L achieved 99.9% kill within 8 h at all HS concentrations; early killing activity was slightly attenuated at higher HS concentrations.
PloS one  •  2016  |  View Paper