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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
drug:
Dapsone
supplement:
Iron, Dietary
Research Papers that Mention the Interaction
“Second, the inadvertent simultaneous administration of low doses of oral iron with dapsone for the prophylaxis of Pneumocystis carinii pneumonia in HIV-positive patients may have been associated with excess mortality.”
Iron status and the outcome of HIV infection: an overview.“The acute intoxication of rats with aniline or dapsone induced a marked increase in the erythrocyte content of free iron and methemoglobin, indicating that the xenobiotics are effective only after biotransformation to toxic metabolites in vivo.”
Hemolytic drugs aniline and dapsone induce iron release in erythrocytes and increase the free iron pool in spleen and liver.
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