supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
drug:
Dantrolene
supplement:
Potassium
Research Papers that Mention the Interaction
“It was shown that … first: developmental, stage of potassium or acetylcholine contracture … inhibited by dantrolene and is not influenced by calcium free medium, therefore we may interpret it as based on a "voltage-dependent Ca release" (VDCR) mechanism of activation, whereas depolarization directly opens the rhyanodin receptor calcium channels.”
[Functioning of the electromechanical connection in the course of the contracture contraction].“Additionally, dantrolene decreases proteolysis in the presence of depolarizing levels of potassium , while it has no effect on degradation in normal media.”
“The peak tensions of twitch, tetanus and potassium contracture were significantly inhibited by dantrolene , without affecting the magnitude of resting potential, the amplitude and duration of action potential and the negative afterpotential.”
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback