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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
Research Papers that Mention the Interaction
“At the 12-month follow-up, sustained response was achieved more frequently in patients receiving ATRA plus danazol than in those receiving danazol monotherapy (28 [62%] of 45 vs 12 [25%] of 48; odds ratio 4·94, 95% CI 2·03-12·02, p=0·00037).”
“Only two grade 3 adverse events were reported: one (2%) patient receiving ATRA plus danazol with dry skin, and one (2%) patient receiving danazol monotherapy with liver injury.”
Oral all-trans retinoic acid plus danazol versus danazol as second-line treatment in adults with primary immune thrombocytopenia: a multicentre, randomised, open-label, phase 2 trial.“RTBM1 and SH-SY5Y cells undergo marked morphological changes associated with a remarkable induction of DAN gene expression when exposed to RA.”
“The forced expression of DAN gene enhanced the neurite extension in the presence of RA , suggesting that DAN gene product might contain some regulatory role(s) in the RA-induced cellular differentiation in neuroblastoma cells.”
“28 (62%) of 45 patients given ATRA plus danazol responded to treatment, compared with 12 (25%) of 48 given danazol (p=0·00037).”
“However, a rapid response would be desirable if danazol in combination with ATRA shall become an important therapeutic option De nn is Ku nk el M icr os co py /S cie nc e Ph ot o Li br ar y”
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