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Discover Supplement-Drug Interactions
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Last Updated: 5 years ago
supplement:
Daidzein
supplement:
Soy Isoflavones
Research Papers that Mention the Interaction
“After the evening intake … dose of an isoflavone-rich soy protein isolate drink, the early morning … levels of genistein and daidzein were higher in seven dialysis patients than in eight healthy subjects (genistein 1271+/-321 … 425+/-104, P<0.05; daidzein 1304+/-352 versus 292+/-78, P<0.05).”
Serum levels and metabolic clearance of the isoflavones genistein and daidzein in hemodialysis patients.“Thus, the soy isoflavone daidzein recapitulated seizure induction in vivo and altered AβPP expression in vitro.”
“The observation that major human metabolites of DAI exhibit estrogenic and genotoxic potential may be of relevance for the safety evaluation of diets containing soy isoflavones.”
“In analyses conducted in cases and controls separately, levels of plasma genistein, daidzein and total isoflavones increased with increasing levels of self-reported intake of soy isoflavones.”
“Our major hypothesis was that dietary exposure to the soy phytoestrogen DAZ could modulate the immune responses toward a protective effect and lead to improved metabolic functions (such as glucose metabolism).”
Isoflavone daidzein regulates immune responses in the B6C3F1 and non-obese diabetic (NOD) mice.
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