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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Daidzein
supplement:
Equol, (-)-
Research Papers that Mention the Interaction
“The biotransformation kinetics of daidzein by the mixed cultures showed that the production of S-equol from daidzein was significantly enhanced, as compared to the production of S-equol from dihydrodaidzein by Eggerthella sp. Julong 732 alone.”
Production of phytoestrogen S-equol from daidzein in mixed culture of two anaerobic bacteria“ Dietary daidzein increased serum and bile concentrations of S-equol to far higher levels than those of daidzein.”
“ Dietary daidzein significantly increased serum and bile concentrations of S-equol in a time-dependent manner, but not those of daidzein.”
Dietary daidzein induces accumulation of S-equol in enterohepatic circulation to far higher levels than that of daidzein in female rats with and without ovariectomy.“The introduction of the DHDR P212A mutation increased the (S)-equol productivity from 59.0 mg/liter/h to 69.8 mg/liter/h in the whole-cell reaction.”
P212A Mutant of Dihydrodaidzein Reductase Enhances (S)-Equol Production and Enantioselectivity in a Recombinant Escherichia coli Whole-Cell Reaction System
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