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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Dactinomycin
supplement:
Tryptophan
Research Papers that Mention the Interaction
“ Tryptophan administered to fasted rats or to rats pretreated with puromycin or actinomycin D caused significant increases in the activity of Mg2+-dependent nucleoside triphosphatase in the hepatic nuclear envelopes over that in controls.”
Effect of Tryptophan on Nuclear Envelope Nucleoside Triphosphatase Activity in Rat Liver 1“When the adrenalectomized … were pretreated with actinomycin-D , a further … of tryptophan caused only a 15–30% increment in [3H]leucine incorporation into ferritin, albumin, transferrin, and fibrinogen, whereas in the … of the antibiotic, tryptophan resulted in a 45–70% increment of the same, compared to water-fed controls.”
“ Actinomycin D prevents the induction of the enzyme by cortisol and tryptophan.”
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