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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
drug:
Dactinomycin
supplement:
Ovalbumin
Research Papers that Mention the Interaction
“Mice on a GAFD or on a G−AD and sensitized with OVA developed milder AHR compared to mice fed a G+AD or an AD.”
Dietary wheat amylase trypsin inhibitors exacerbate murine allergic airway inflammation“ Actinomycin D , ethionine, thioacetamide (non-mutagenic in the Ames Salmonella test) and kepone are known to increase serum progesterone concentrations and induce synthesis of ovalbumin in chicks.”
“In vivo administration of actinomycin D to chicks led to a 65% increase in the rate of ovalbumin synthesis in culture with no change in total or polysomal mRNA levels, providing direct evidence that this drug increases the rate of ovalbumin mRNA translation.”
“Furthermore, actinomycin D increased the absolute rate of ovalbumin and conalbumin synthesis compared to untreated controls, despite a small decrease in the number of polysomes and the concentration of total ovalbumin mRNA.”
“ Actinomycin D , at a dose of 5 mg per kg, blocks the estrogen-mediated increase in isotope incorporation into RNA, total protein, and ovalbumin.”
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