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“The increase in GST following cadmium or manganese administration was blocked by prior administration of actinomycin D , indicative of a possible transcription-dependent response.”
“If Mn was added to 4-day-old nitrogen-limited Mn-deficient cultures, extracellular MnP activity appeared after 6 h and reached a maximum after 18 h. Both actinomycin D and cycloheximide inhibited the induction of MnP activity by Mn.”