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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Dactinomycin and Iron, Dietary

Research Papers that Mention the Interaction

Actinomycin D had no inhibitory effect, after administration of iron, on [(14)C]leucine incorporation into ferritin but appeared to augment the effect of iron on ferritin synthesis.
The Biochemical journal  •  1970  |  View Paper
This induced uptake of iron is inhibited by actinomycin D , puromycin, and cycloheximide, indicating that RNA synthesis and protein synthesis are required for expression of this erythropoietin effect.
Biochimica et biophysica acta  •  1969  |  View Paper
a) Actinomycin D inhibits the response to iron. (
The Journal of biological chemistry  •  1968  |  View Paper
Actinomycin D inhibited the stimulatory effect of iron , indicating that derepression of genes and the synthesis of messenger RNA are involved in the regulatory response to the metal.
Nature  •  1966  |  View Paper