supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
drug:
Dactinomycin
supplement:
Iron, Dietary
Research Papers that Mention the Interaction
“ Actinomycin D had no inhibitory effect, after administration of iron, on [(14)C]leucine incorporation into ferritin but appeared to augment the effect of iron on ferritin synthesis.”
Effect of actinomycin D, cycloheximide, and acute blood loss of ferritin synthesis in rat liver.“This induced uptake of iron is inhibited by actinomycin D , puromycin, and cycloheximide, indicating that RNA synthesis and protein synthesis are required for expression of this erythropoietin effect.”
“a) Actinomycin D inhibits the response to iron. (”
“ Actinomycin D inhibited the stimulatory effect of iron , indicating that derepression of genes and the synthesis of messenger RNA are involved in the regulatory response to the metal.”
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback