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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Dactinomycin and Delphinidin

supplement:

Delphinidin

Research Papers that Mention the Interaction

Based on flow cytometry, terminal deoxynucleotidyl transferase‐mediated dUTP … detection of mitochondrial cytochrome c release, we show that delphinidin (10−2 g l−1) alone had no effect … apoptosis, but it significantly reduced apoptosis elicited by actinomycin D (1 μg ml−1, 24 h) … μg ml−1, 18 h).
Finally, delphinidin alone had no effect on cytosolic‐free calcium ([Ca2+]i), but normalized the changes in [Ca2+]i produced by actinomycin D towards the control values, suggesting that the antiapoptotic effect of delphinidin is associated with the maintenance of [Ca2+]i in the physiological range.
British journal of pharmacology  •  2003  |  View Paper