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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Dactinomycin
supplement:
Delphinidin
Research Papers that Mention the Interaction
“Based on flow cytometry, terminal deoxynucleotidyl transferase‐mediated dUTP … detection of mitochondrial cytochrome c release, we show that delphinidin (10−2 g l−1) alone had no effect … apoptosis, but it significantly reduced apoptosis elicited by actinomycin D (1 μg ml−1, 24 h) … μg ml−1, 18 h).”
“Finally, delphinidin alone had no effect on cytosolic‐free calcium ([Ca2+]i), but normalized the changes in [Ca2+]i produced by actinomycin D towards the control values, suggesting that the antiapoptotic effect of delphinidin is associated with the maintenance of [Ca2+]i in the physiological range.”
Delphinidin, an active compound of red wine, inhibits endothelial cell apoptosis via nitric oxide pathway and regulation of calcium homeostasis
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