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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Dacarbazine
supplement:
Vitamin D
Research Papers that Mention the Interaction
“This study presents data indicating that … of the hormonally active form of vitamin D , 1α,25-dihydroxyvitamin D3 [1α,25(OH)2D3], its non-calcemic analogues 20S-hydroxyvitamin D3 and 21-… well as the low-calcemic synthetic analog calcipotriol, modulate the efficacy of the anticancer drugs cisplatin and dacarbazine.”
“ Vitamin D exhibited modulatory effects on the cells treated with dacarbazine , decreasing the half maximal inhibitory concentration (IC50) for the drug, stimulating G1/G0 arrest and causing a marked decrease in Δψm.”
Vitamin D and its low calcemic analogs modulate the anticancer properties of cisplatin and dacarbazine in the human melanoma A375 cell line
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