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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Dacarbazine
supplement:
Tretinoin
Research Papers that Mention the Interaction
“CONCLUSION Collectively, combined treatment with AT A an d dac arbazine in duced more apoptosis and enhanced the cell cycle arrest of CD117+ melanoma cells.”
“Here, we aim to improve response to dacarbazine therapy by pretreatment with all-trans retinoic acid (ATRA) in CD117+ melanoma cells.”
“There was an indication that the combination of ATRA with dacarbazine (ATRA/dacarbazine) caused more apoptosis and necrosis in the melanoma cells (P<0.05).”
“These results suggested that ATRA increased the sensitivity of melanoma cells to the effect of dacarbazine.”
In Vitro Anticancer Effects of All-trans Retinoic Acid in Combination with Dacarbazine against CD117+ Melanoma Cells.“The discovery of all-trans-retinoic acid has changed the course of APL treatment by reducing the onset of DIC and inducing a complete and durable remission in more than 90% of patients.”
“We demonstrated that the simultaneous delivery of DBZ and ATRA could effectively reduce cell proliferation in a concentration-dependent manner.”
Co-delivery of Dacarbazine and All-Trans Retinoic Acid (ATRA) Using Lipid Nanoformulations for Synergistic Antitumor Efficacy Against Malignant Melanoma
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