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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Dacarbazine and Tretinoin

supplement:

Tretinoin

Research Papers that Mention the Interaction

CONCLUSION Collectively, combined treatment with AT A an d dac arbazine in duced more apoptosis and enhanced the cell cycle arrest of CD117+ melanoma cells.
Here, we aim to improve response to dacarbazine therapy by pretreatment with all-trans retinoic acid (ATRA) in CD117+ melanoma cells.
There was an indication that the combination of ATRA with dacarbazine (ATRA/dacarbazine) caused more apoptosis and necrosis in the melanoma cells (P<0.05).
These results suggested that ATRA increased the sensitivity of melanoma cells to the effect of dacarbazine.
Drug research  •  2020  |  View Paper
The discovery of all-trans-retinoic acid has changed the course of APL treatment by reducing the onset of DIC and inducing a complete and durable remission in more than 90% of patients.
International journal of hematology  •  2004  |  View Paper
We demonstrated that the simultaneous delivery of DBZ and ATRA could effectively reduce cell proliferation in a concentration-dependent manner.
Nanoscale Research Letters  •  2020  |  View Paper