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Discover Supplement-Drug Interactions

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Last Updated: 5 months ago

Possible Interaction: Dacarbazine and Cupric Cation

supplement:

Cupric Cation

Research Papers that Mention the Interaction

The interaction of Dac with dsDNA in the presence of Cu(II ) leads to a much stronger intercalation.
Journal of pharmaceutical and biomedical analysis  •  2014  |  View Paper
Electron spin resonance (ESR) spin-trapping experiments were performed to … radical species generated from UVA-irradiated DTIC.ResultsUVA-irradiated DTIC caused DNA damage at guanine residues, especially at the 5′-GGT-3′ sequence in the presence of Cu(II ) and also induced 8-oxodG generation in calf thymus DNA.
Pharmaceutical Research  •  2007  |  View Paper